N'-((2-(6-bromo-2-oxo-2H-chromen-3-yl)-1H-indol-3-yl)methylene)benzohydrazide as a probable Bcl-2/Bcl-xL inhibitor with apoptotic and anti-metastatic potential.

Kamath, Pooja R

N'-((2-(6-bromo-2-oxo-2H-chromen-3-yl)-1H-indol-3-yl)methylene)benzohydrazide as a probable Bcl-2/Bcl-xL inhibitor with apoptotic and anti-metastatic potential. [electronic resource] - European journal of medicinal chemistry Sep 2016 - 134-47 p. digital

Publication Type: Journal Article

1768-3254

10.1016/j.ejmech.2016.05.010 doi


Apoptosis--drug effects
Breast Neoplasms--drug therapy
Cell Cycle Checkpoints--drug effects
Cell Line, Tumor
Cell Survival--drug effects
Female
Humans
Hydrazines--chemistry
Molecular Docking Simulation
Neoplasm Metastasis--drug therapy
Proto-Oncogene Proteins c-bcl-2--antagonists & inhibitors
bcl-X Protein--antagonists & inhibitors