Oxymatrine protects against sepsis-induced myocardial injury via inhibition of the TNF-α/p38-MAPK/caspase-3 signaling pathway.

Zhang, Minghao

Oxymatrine protects against sepsis-induced myocardial injury via inhibition of the TNF-α/p38-MAPK/caspase-3 signaling pathway. [electronic resource] - Molecular medicine reports Jul 2016 - 551-9 p. digital

Publication Type: Journal Article

1791-3004

10.3892/mmr.2016.5250 doi


Alkaloids--pharmacology
Animals
Apoptosis--drug effects
Biomarkers
Caspase 3--genetics
Disease Models, Animal
Gene Expression Regulation--drug effects
Heart Diseases--diagnosis
Heart Function Tests
Male
Myocardium--metabolism
Quinolizines--pharmacology
Rats
Sepsis--complications
Signal Transduction--drug effects
Tumor Necrosis Factor-alpha--genetics
p38 Mitogen-Activated Protein Kinases--genetics