Netrin-1 attenuates the progression of renal dysfunction by blocking endothelial-to-mesenchymal transition in the 5/6 nephrectomy rat model.

Bai, Jiuxu

Netrin-1 attenuates the progression of renal dysfunction by blocking endothelial-to-mesenchymal transition in the 5/6 nephrectomy rat model. [electronic resource] - BMC nephrology 05 2016 - 47 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1471-2369

10.1186/s12882-016-0260-4 doi


Actins--genetics
Animals
Blood Urea Nitrogen
Creatinine--blood
Endothelium--physiopathology
Epithelial-Mesenchymal Transition--genetics
Fibrosis
Kidney--pathology
Male
Nephrectomy
Netrin-1--genetics
Platelet Endothelial Cell Adhesion Molecule-1--genetics
RNA, Messenger--metabolism
Rats
Rats, Sprague-Dawley
Renal Insufficiency, Chronic--pathology
Signal Transduction
Snail Family Transcription Factors--genetics
Transforming Growth Factor beta--metabolism