Pioglitazone, a Peroxisome Proliferator-Activated Receptor x03B3; Agonist, Ameliorates Chronic Kidney Disease by Enhancing Antioxidative Capacity and Attenuating Angiogenesis in the Kidney of a 5/6 Nephrectomized Rat Model.

Sun, Li

Pioglitazone, a Peroxisome Proliferator-Activated Receptor x03B3; Agonist, Ameliorates Chronic Kidney Disease by Enhancing Antioxidative Capacity and Attenuating Angiogenesis in the Kidney of a 5/6 Nephrectomized Rat Model. [electronic resource] - Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016 - 1831-40 p. digital

Publication Type: Journal Article

1421-9778

10.1159/000443121 doi


Animals
Antioxidants--metabolism
Blood Urea Nitrogen
Creatinine--blood
Disease Models, Animal
Down-Regulation--drug effects
Hypoxia-Inducible Factor 1, alpha Subunit--metabolism
Kidney--blood supply
Malondialdehyde--analysis
Neovascularization, Physiologic--drug effects
Nephrectomy
Nitric Oxide--analysis
PPAR gamma--agonists
Pioglitazone
Rats
Rats, Sprague-Dawley
Renal Insufficiency, Chronic--drug therapy
Superoxide Dismutase--analysis
Thiazolidinediones--pharmacology
Vascular Endothelial Growth Factor A--blood