A Small Dibromotyrosine Derivative Purified From Pseudoceratina Sp. Suppresses TGF-β Responsiveness by Inhibiting TGF-β Type I Receptor Serine/Threonine Kinase Activity.

Chen, Chun-Lin

A Small Dibromotyrosine Derivative Purified From Pseudoceratina Sp. Suppresses TGF-β Responsiveness by Inhibiting TGF-β Type I Receptor Serine/Threonine Kinase Activity. [electronic resource] - Journal of cellular biochemistry 12 2016 - 2800-2814 p. digital

Publication Type: Journal Article

1097-4644

10.1002/jcb.25581 doi


Acetonitriles--pharmacology
Animals
Apoptosis--drug effects
Blotting, Western
Cell Proliferation--drug effects
Cyclohexanones--pharmacology
Enzyme Inhibitors--pharmacology
Epithelial-Mesenchymal Transition--drug effects
Fluorescent Antibody Technique
Humans
Lung Neoplasms--drug therapy
Phosphorylation--drug effects
Porifera--chemistry
Protein Serine-Threonine Kinases--antagonists & inhibitors
RNA, Messenger--genetics
Real-Time Polymerase Chain Reaction
Receptor, Transforming Growth Factor-beta Type I
Receptors, Transforming Growth Factor beta--antagonists & inhibitors
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--drug effects
Smad Proteins--genetics
Transforming Growth Factor beta--pharmacology
Tumor Cells, Cultured
Tyrosine--analogs & derivatives