Sleep deprivation impairs memory by attenuating mTORC1-dependent protein synthesis.
Tudor, Jennifer C
Sleep deprivation impairs memory by attenuating mTORC1-dependent protein synthesis. [electronic resource] - Science signaling 04 2016 - ra41 p. digital
Publication Type: Journal Article
1937-9145
10.1126/scisignal.aad4949 doi
Animals
Blotting, Western
Cognition
Cytoskeletal Proteins--metabolism
Endoplasmic Reticulum Chaperone BiP
Enzyme-Linked Immunosorbent Assay
Eukaryotic Initiation Factor-4E--metabolism
Eukaryotic Initiation Factor-4G--metabolism
Eukaryotic Initiation Factors--metabolism
Heat-Shock Proteins--metabolism
Hippocampus--metabolism
Immunohistochemistry
Male
Mechanistic Target of Rapamycin Complex 1--metabolism
Memory Disorders--metabolism
Mice
Mice, Inbred C57BL
Nerve Tissue Proteins--metabolism
Neurons--metabolism
Phosphorylation
Protein Biosynthesis
Puromycin--pharmacology
Real-Time Polymerase Chain Reaction
Sleep Deprivation--metabolism
Statistics, Nonparametric
Sleep deprivation impairs memory by attenuating mTORC1-dependent protein synthesis. [electronic resource] - Science signaling 04 2016 - ra41 p. digital
Publication Type: Journal Article
1937-9145
10.1126/scisignal.aad4949 doi
Animals
Blotting, Western
Cognition
Cytoskeletal Proteins--metabolism
Endoplasmic Reticulum Chaperone BiP
Enzyme-Linked Immunosorbent Assay
Eukaryotic Initiation Factor-4E--metabolism
Eukaryotic Initiation Factor-4G--metabolism
Eukaryotic Initiation Factors--metabolism
Heat-Shock Proteins--metabolism
Hippocampus--metabolism
Immunohistochemistry
Male
Mechanistic Target of Rapamycin Complex 1--metabolism
Memory Disorders--metabolism
Mice
Mice, Inbred C57BL
Nerve Tissue Proteins--metabolism
Neurons--metabolism
Phosphorylation
Protein Biosynthesis
Puromycin--pharmacology
Real-Time Polymerase Chain Reaction
Sleep Deprivation--metabolism
Statistics, Nonparametric