OCT-4: a novel estrogen receptor-α collaborator that promotes tamoxifen resistance in breast cancer cells.

Bhatt, S

OCT-4: a novel estrogen receptor-α collaborator that promotes tamoxifen resistance in breast cancer cells. [electronic resource] - Oncogene 11 2016 - 5722-5734 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1476-5594

10.1038/onc.2016.105 doi


Animals
Antineoplastic Agents, Hormonal--pharmacology
Binding Sites
Breast Neoplasms--drug therapy
Cell Line, Tumor
Cell Proliferation
Cell Transformation, Neoplastic--genetics
Disease Models, Animal
Drug Resistance, Neoplasm--genetics
Estrogen Receptor alpha--metabolism
Female
Gene Expression
Gene Expression Regulation, Neoplastic--drug effects
Gene Knockdown Techniques
Homeodomain Proteins--metabolism
Humans
Mice
Models, Biological
Nucleotide Motifs
Octamer Transcription Factor-3--genetics
Phosphorylation
Protein Binding
Response Elements
S-Phase Kinase-Associated Proteins--metabolism
Signal Transduction
Tamoxifen--pharmacology
Transcription Factors--metabolism
Xenograft Model Antitumor Assays
p38 Mitogen-Activated Protein Kinases--metabolism