Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria.

Richter, Benjamin

Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Apr 2016 - 4039-44 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1091-6490

10.1073/pnas.1523926113 doi


Autophagy
Cell Cycle Proteins
HeLa Cells
Humans
Membrane Transport Proteins
Mitochondria--metabolism
Phosphorylation
Protein Binding
Protein Serine-Threonine Kinases--metabolism
Transcription Factor TFIIIA--metabolism
Ubiquitin--metabolism