An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model.
Jennis, Matthew
An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model. [electronic resource] - Genes & development Apr 2016 - 918-30 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
1549-5477
10.1101/gad.275891.115 doi
Animals
Black People--genetics
Carcinoma, Hepatocellular--genetics
Cell Death--drug effects
Cell Line
Cisplatin--pharmacology
Codon--chemistry
Disease Models, Animal
Genes, p53--genetics
Humans
Mice
Mice, Inbred C57BL
Neoplasms--genetics
Polymorphism, Single Nucleotide
Protein Binding--genetics
Risk Factors
Transcriptional Activation--drug effects
Tumor Suppressor Protein p53--genetics
An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model. [electronic resource] - Genes & development Apr 2016 - 918-30 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
1549-5477
10.1101/gad.275891.115 doi
Animals
Black People--genetics
Carcinoma, Hepatocellular--genetics
Cell Death--drug effects
Cell Line
Cisplatin--pharmacology
Codon--chemistry
Disease Models, Animal
Genes, p53--genetics
Humans
Mice
Mice, Inbred C57BL
Neoplasms--genetics
Polymorphism, Single Nucleotide
Protein Binding--genetics
Risk Factors
Transcriptional Activation--drug effects
Tumor Suppressor Protein p53--genetics