Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199.

García, Carolina Paola

Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199. [electronic resource] - PloS one 2016 - e0152607 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0152607 doi


Aniline Compounds--pharmacology
Ataxia Telangiectasia Mutated Proteins--metabolism
Bridged Bicyclo Compounds, Heterocyclic--pharmacology
Camptothecin--pharmacology
Cell Line
Human Embryonic Stem Cells--cytology
Humans
Induced Pluripotent Stem Cells--cytology
Neural Stem Cells--cytology
Proto-Oncogene Proteins c-bcl-2--metabolism
Sulfonamides--pharmacology
Tumor Suppressor Protein p53--metabolism
bcl-X Protein--metabolism