Harmine induces cell cycle arrest and mitochondrial pathway-mediated cellular apoptosis in SW620 cells via inhibition of the Akt and ERK signaling pathways.

Liu, Jiming

Harmine induces cell cycle arrest and mitochondrial pathway-mediated cellular apoptosis in SW620 cells via inhibition of the Akt and ERK signaling pathways. [electronic resource] - Oncology reports Jun 2016 - 3363-70 p. digital

Publication Type: Journal Article

1791-2431

10.3892/or.2016.4695 doi


Apoptosis--drug effects
Cell Cycle Checkpoints--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Colorectal Neoplasms--drug therapy
Extracellular Signal-Regulated MAP Kinases--antagonists & inhibitors
Harmine--pharmacology
Humans
MAP Kinase Signaling System--drug effects
Membrane Potential, Mitochondrial--drug effects
Proto-Oncogene Proteins c-akt--antagonists & inhibitors