DRP1-dependent apoptotic mitochondrial fission occurs independently of BAX, BAK and APAF1 to amplify cell death by BID and oxidative stress.
Oettinghaus, Björn
DRP1-dependent apoptotic mitochondrial fission occurs independently of BAX, BAK and APAF1 to amplify cell death by BID and oxidative stress. [electronic resource] - Biochimica et biophysica acta Aug 2016 - 1267-1276 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0006-3002
10.1016/j.bbabio.2016.03.016 doi
Animals
Apoptosis--drug effects
Apoptotic Protease-Activating Factor 1--deficiency
BH3 Interacting Domain Death Agonist Protein--genetics
Cell Line
Cytochromes c--metabolism
Dynamins--deficiency
Fibroblasts--cytology
Gene Expression Regulation
Hydrogen Peroxide--pharmacology
Mice
Mice, Knockout
Mitochondrial Dynamics--drug effects
Oxidative Stress
Signal Transduction
Staurosporine--pharmacology
Thapsigargin--pharmacology
bcl-2 Homologous Antagonist-Killer Protein--deficiency
bcl-2-Associated X Protein--deficiency
DRP1-dependent apoptotic mitochondrial fission occurs independently of BAX, BAK and APAF1 to amplify cell death by BID and oxidative stress. [electronic resource] - Biochimica et biophysica acta Aug 2016 - 1267-1276 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0006-3002
10.1016/j.bbabio.2016.03.016 doi
Animals
Apoptosis--drug effects
Apoptotic Protease-Activating Factor 1--deficiency
BH3 Interacting Domain Death Agonist Protein--genetics
Cell Line
Cytochromes c--metabolism
Dynamins--deficiency
Fibroblasts--cytology
Gene Expression Regulation
Hydrogen Peroxide--pharmacology
Mice
Mice, Knockout
Mitochondrial Dynamics--drug effects
Oxidative Stress
Signal Transduction
Staurosporine--pharmacology
Thapsigargin--pharmacology
bcl-2 Homologous Antagonist-Killer Protein--deficiency
bcl-2-Associated X Protein--deficiency