Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex.
Garibaldi, F
Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex. [electronic resource] - Oncogene 07 2016 - 3760-70 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-5594
10.1038/onc.2016.51 doi
Apoptosis--genetics
Blotting, Western
Cell Cycle--genetics
Cell Line, Tumor
Cell Proliferation--genetics
DEAD-box RNA Helicases--genetics
Gene Expression Regulation, Neoplastic
HCT116 Cells
HEK293 Cells
HT29 Cells
Humans
Membrane Potential, Mitochondrial--genetics
MicroRNAs--genetics
Mutation
Neoplasms--genetics
Protein Binding
RNA Interference
RNA Processing, Post-Transcriptional
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--genetics
Tumor Suppressor Protein p53--genetics
Mutant p53 inhibits miRNA biogenesis by interfering with the microprocessor complex. [electronic resource] - Oncogene 07 2016 - 3760-70 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-5594
10.1038/onc.2016.51 doi
Apoptosis--genetics
Blotting, Western
Cell Cycle--genetics
Cell Line, Tumor
Cell Proliferation--genetics
DEAD-box RNA Helicases--genetics
Gene Expression Regulation, Neoplastic
HCT116 Cells
HEK293 Cells
HT29 Cells
Humans
Membrane Potential, Mitochondrial--genetics
MicroRNAs--genetics
Mutation
Neoplasms--genetics
Protein Binding
RNA Interference
RNA Processing, Post-Transcriptional
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--genetics
Tumor Suppressor Protein p53--genetics