Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles.

Bueno, Ana B

Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles. [electronic resource] - The Journal of biological chemistry May 2016 - 10700-15 p. digital

Publication Type: Journal Article

1083-351X

10.1074/jbc.M115.696039 doi


Allosteric Regulation
Animals
Cell Line
Cyclic AMP--metabolism
Glucagon-Like Peptide-1 Receptor--chemistry
Glucose--metabolism
HEK293 Cells
Humans
Insulin--metabolism
Insulin Secretion
Insulin-Secreting Cells--drug effects
Islets of Langerhans--drug effects
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Mutant Proteins--chemistry
Pyrimidines--chemistry
Rats
Signal Transduction--drug effects
Glucagon-Like Peptide-1 Receptor Agonists