αB-Crystallin Interacts with Nav1.5 and Regulates Ubiquitination and Internalization of Cell Surface Nav1.5.

Huang, Yuan

αB-Crystallin Interacts with Nav1.5 and Regulates Ubiquitination and Internalization of Cell Surface Nav1.5. [electronic resource] - The Journal of biological chemistry May 2016 - 11030-41 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M115.695080 doi


Animals
Cell Line
Cell Membrane--metabolism
Endosomal Sorting Complexes Required for Transport--chemistry
Gene Knockdown Techniques
HEK293 Cells
Humans
Mutant Proteins--chemistry
Myocardium--metabolism
NAV1.5 Voltage-Gated Sodium Channel--chemistry
Nedd4 Ubiquitin Protein Ligases
Protein Binding
Protein Interaction Domains and Motifs
Protein Stability
Protein Transport
Rats
Recombinant Proteins--chemistry
Ubiquitin-Protein Ligases--chemistry
Ubiquitination
alpha-Crystallin B Chain--chemistry