Assessment of cytochrome P450 inhibition and induction potential of lupeol and betulin in rat liver microsomes.

Seervi, Madhav

Assessment of cytochrome P450 inhibition and induction potential of lupeol and betulin in rat liver microsomes. [electronic resource] - Drug metabolism and personalized therapy 06 2016 - 115-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2363-8915

10.1515/dmpt-2015-0043 doi


Animals
Cytochrome P-450 CYP1A2--metabolism
Cytochrome P-450 CYP2C9--metabolism
Cytochrome P-450 CYP3A--metabolism
Cytochrome P-450 Enzyme Inhibitors--pharmacology
Dose-Response Relationship, Drug
Enzyme Induction--drug effects
Herb-Drug Interactions
Male
Microsomes, Liver--enzymology
Pentacyclic Triterpenes--pharmacology
Rats
Triterpenes--pharmacology