Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis.

Gu, Hongmei

Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis. [electronic resource] - FASEB journal : official publication of the Federation of American Societies for Experimental Biology 06 2016 - 2336-50 p. digital

Publication Type: Journal Article

1530-6860

10.1096/fj.201500044 doi


Aged
Aged, 80 and over
Animals
Antibiotics, Antineoplastic--toxicity
Bleomycin--toxicity
Cell Line
Collagen Type I, alpha 1 Chain
Complement Membrane Attack Complex--genetics
Down-Regulation
Fibroblasts--metabolism
Gene Expression Regulation--physiology
Humans
Lung Injury--chemically induced
Mice
Mice, Inbred C57BL
Middle Aged
Pulmonary Fibrosis--chemically induced
RNA Interference
Receptor, Anaphylatoxin C5a--genetics
Receptors, Complement--genetics
Signal Transduction--physiology
Transforming Growth Factor beta--genetics
Up-Regulation