Disruption of Glut1 in Hematopoietic Stem Cells Prevents Myelopoiesis and Enhanced Glucose Flux in Atheromatous Plaques of ApoE(-/-) Mice.

Sarrazy, Vincent

Disruption of Glut1 in Hematopoietic Stem Cells Prevents Myelopoiesis and Enhanced Glucose Flux in Atheromatous Plaques of ApoE(-/-) Mice. [electronic resource] - Circulation research Apr 2016 - 1062-77 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1524-4571

10.1161/CIRCRESAHA.115.307599 doi


Animals
Aorta, Thoracic--metabolism
Apolipoproteins E--deficiency
Bone Marrow Transplantation
Cell Division
Cytokine Receptor Common beta Subunit--physiology
Disease Progression
Energy Metabolism
Gene Expression Regulation
Glucose--metabolism
Glucose Transporter Type 1--deficiency
Glycolysis
Hematopoietic Stem Cells--metabolism
Hypercholesterolemia--genetics
Hypoxia-Inducible Factor 1, alpha Subunit--deficiency
Metformin--pharmacology
Mice
Mice, Inbred C57BL
Mice, Knockout
Multipotent Stem Cells--metabolism
Myelopoiesis--physiology
Plaque, Atherosclerotic--metabolism
RNA, Messenger--biosynthesis
Receptors, Interleukin-3--antagonists & inhibitors
Spleen--metabolism
Tyrphostins--pharmacology