Cdc7 is a potent anti-cancer target in pancreatic cancer due to abrogation of the DNA origin activation checkpoint.

Huggett, Matthew T

Cdc7 is a potent anti-cancer target in pancreatic cancer due to abrogation of the DNA origin activation checkpoint. [electronic resource] - Oncotarget Apr 2016 - 18495-507 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1949-2553

10.18632/oncotarget.7611 doi


Adenocarcinoma--drug therapy
Cell Cycle Proteins--antagonists & inhibitors
Cell Line, Tumor
Cohort Studies
DNA Replication
G1 Phase Cell Cycle Checkpoints--drug effects
Humans
Molecular Targeted Therapy
Pancreatic Neoplasms--drug therapy
Piperidones--pharmacology
Protein Serine-Threonine Kinases--antagonists & inhibitors
Pyrroles--pharmacology
Transfection