PRMT5-Mediated Methylation of NF-κB p65 at Arg174 Is Required for Endothelial CXCL11 Gene Induction in Response to TNF-α and IFN-γ Costimulation.
Harris, Daniel P
PRMT5-Mediated Methylation of NF-κB p65 at Arg174 Is Required for Endothelial CXCL11 Gene Induction in Response to TNF-α and IFN-γ Costimulation. [electronic resource] - PloS one 2016 - e0148905 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1932-6203
10.1371/journal.pone.0148905 doi
Cells, Cultured
Chemokine CXCL11--genetics
Endothelial Cells--drug effects
Gene Expression Regulation--drug effects
Gene Knockdown Techniques
Human Umbilical Vein Endothelial Cells
Humans
Interferon-gamma--pharmacology
Methylation
Mutation
Promoter Regions, Genetic
Protein-Arginine N-Methyltransferases--genetics
Transcription Factor RelA--metabolism
Tumor Necrosis Factor-alpha--pharmacology
PRMT5-Mediated Methylation of NF-κB p65 at Arg174 Is Required for Endothelial CXCL11 Gene Induction in Response to TNF-α and IFN-γ Costimulation. [electronic resource] - PloS one 2016 - e0148905 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1932-6203
10.1371/journal.pone.0148905 doi
Cells, Cultured
Chemokine CXCL11--genetics
Endothelial Cells--drug effects
Gene Expression Regulation--drug effects
Gene Knockdown Techniques
Human Umbilical Vein Endothelial Cells
Humans
Interferon-gamma--pharmacology
Methylation
Mutation
Promoter Regions, Genetic
Protein-Arginine N-Methyltransferases--genetics
Transcription Factor RelA--metabolism
Tumor Necrosis Factor-alpha--pharmacology