Altered S-nitrosothiol homeostasis provides a survival advantage to breast cancer cells in HER2 tumors and reduces their sensitivity to trastuzumab.

Cañas, Amanda

Altered S-nitrosothiol homeostasis provides a survival advantage to breast cancer cells in HER2 tumors and reduces their sensitivity to trastuzumab. [electronic resource] - Biochimica et biophysica acta 04 2016 - 601-610 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-3002

10.1016/j.bbadis.2016.02.005 doi


Breast Neoplasms--drug therapy
Cell Survival--drug effects
Drug Resistance, Neoplasm--drug effects
Female
Homeostasis--drug effects
Humans
MCF-7 Cells
Receptor, ErbB-2--metabolism
S-Nitrosothiols--metabolism
Trastuzumab--pharmacology