The highly selective orexin/hypocretin 1 receptor antagonist GSK1059865 potently reduces ethanol drinking in ethanol dependent mice.

Lopez, Marcelo F

The highly selective orexin/hypocretin 1 receptor antagonist GSK1059865 potently reduces ethanol drinking in ethanol dependent mice. [electronic resource] - Brain research Apr 2016 - 74-80 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1872-6240

10.1016/j.brainres.2016.01.049 doi


Alcohol Drinking--drug therapy
Aminopyridines--therapeutic use
Analysis of Variance
Animals
Dose-Response Relationship, Drug
Drinking Behavior--drug effects
Ethanol--administration & dosage
Male
Mice
Mice, Inbred C57BL
Orexin Receptor Antagonists--therapeutic use
Piperidines--therapeutic use
Sucrose--administration & dosage