Irsogladine maleate, a gastric mucosal protectant, suppresses intestinal polyp development in Apc-mutant mice.

Onuma, Wakana

Irsogladine maleate, a gastric mucosal protectant, suppresses intestinal polyp development in Apc-mutant mice. [electronic resource] - Oncotarget Feb 2016 - 8640-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1949-2553

10.18632/oncotarget.7082 doi


Animals
Anti-Ulcer Agents--pharmacology
Apoptosis--drug effects
Blotting, Western
Cell Proliferation--drug effects
Cells, Cultured
Disease Models, Animal
Gastric Mucosa--drug effects
Genes, APC--physiology
Humans
Immunoenzyme Techniques
Interleukin-1beta--genetics
Interleukin-6--genetics
Intestinal Polyps--pathology
Male
Mice
Mice, Inbred C57BL
Mutation--genetics
RNA, Messenger--genetics
Real-Time Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--drug effects
Triazines--pharmacology