Reduced Antiviral Interferon Production in Poorly Controlled Asthma Is Associated With Neutrophilic Inflammation and High-Dose Inhaled Corticosteroids.
Simpson, Jodie L
Reduced Antiviral Interferon Production in Poorly Controlled Asthma Is Associated With Neutrophilic Inflammation and High-Dose Inhaled Corticosteroids. [electronic resource] - Chest Mar 2016 - 704-13 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1931-3543
10.1016/j.chest.2015.12.018 doi
Administration, Inhalation
Adrenal Cortex Hormones--administration & dosage
Adult
Aged
Aged, 80 and over
Asthma--drug therapy
Chemokine CXCL10--immunology
Cross-Sectional Studies
Enzyme-Linked Immunosorbent Assay
Female
Forced Expiratory Volume
Glucocorticoids--administration & dosage
HeLa Cells
Humans
Interferon-alpha--immunology
Interferon-beta--immunology
Interleukin-1beta--immunology
Interleukin-6--immunology
Interleukin-8--immunology
Leukocytes, Mononuclear--drug effects
Male
Middle Aged
Neutrophils--immunology
Rhinovirus--immunology
Severity of Illness Index
Sputum--cytology
Vital Capacity
Young Adult
Reduced Antiviral Interferon Production in Poorly Controlled Asthma Is Associated With Neutrophilic Inflammation and High-Dose Inhaled Corticosteroids. [electronic resource] - Chest Mar 2016 - 704-13 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1931-3543
10.1016/j.chest.2015.12.018 doi
Administration, Inhalation
Adrenal Cortex Hormones--administration & dosage
Adult
Aged
Aged, 80 and over
Asthma--drug therapy
Chemokine CXCL10--immunology
Cross-Sectional Studies
Enzyme-Linked Immunosorbent Assay
Female
Forced Expiratory Volume
Glucocorticoids--administration & dosage
HeLa Cells
Humans
Interferon-alpha--immunology
Interferon-beta--immunology
Interleukin-1beta--immunology
Interleukin-6--immunology
Interleukin-8--immunology
Leukocytes, Mononuclear--drug effects
Male
Middle Aged
Neutrophils--immunology
Rhinovirus--immunology
Severity of Illness Index
Sputum--cytology
Vital Capacity
Young Adult