Development of a long-acting, protein-loaded, redox-active, injectable gel formed by a polyion complex for local protein therapeutics.

Ishii, Shiro

Development of a long-acting, protein-loaded, redox-active, injectable gel formed by a polyion complex for local protein therapeutics. [electronic resource] - Biomaterials Apr 2016 - 210-218 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1878-5905

10.1016/j.biomaterials.2016.01.029 doi


Animals
Antineoplastic Agents--pharmacology
Cell Line, Tumor
Drug Delivery Systems--methods
Fluorescein--chemistry
Gels--chemistry
Immunotherapy
Injections
Interleukin-12--adverse effects
Ions
Male
Mice, Inbred BALB C
Mice, Nude
Micelles
Nitrogen Oxides--chemistry
Oxidation-Reduction
Particle Size
Phase Transition
Polymers--chemistry
Proteins--therapeutic use
Rheology
Temperature
Transition Temperature
Viscosity