EGF816 Exerts Anticancer Effects in Non-Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor.

Jia, Yong

EGF816 Exerts Anticancer Effects in Non-Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor. [electronic resource] - Cancer research Mar 2016 - 1591-602 p. digital

Publication Type: Journal Article

1538-7445

10.1158/0008-5472.CAN-15-2581 doi


Animals
Antineoplastic Agents--pharmacology
Carcinoma, Non-Small-Cell Lung--drug therapy
Cell Line, Tumor
Drug Resistance, Neoplasm--drug effects
ErbB Receptors--metabolism
Female
Lung Neoplasms--drug therapy
Mice
Mice, Nude
Mutation--drug effects
Phosphorylation--drug effects
Rats
Xenograft Model Antitumor Assays--methods