Sustained Nitric Oxide-Releasing Nanoparticles Induce Cell Death in Candida albicans Yeast and Hyphal Cells, Preventing Biofilm Formation In Vitro and in a Rodent Central Venous Catheter Model.

Ahmadi, Mohammed S

Sustained Nitric Oxide-Releasing Nanoparticles Induce Cell Death in Candida albicans Yeast and Hyphal Cells, Preventing Biofilm Formation In Vitro and in a Rodent Central Venous Catheter Model. [electronic resource] - Antimicrobial agents and chemotherapy Apr 2016 - 2185-94 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1098-6596

10.1128/AAC.02659-15 doi


Animals
Antifungal Agents--chemistry
Apoptosis--drug effects
Biofilms--drug effects
Candida albicans--drug effects
Candidiasis--drug therapy
Catheter-Related Infections--drug therapy
Catheterization, Central Venous
Chitosan--chemistry
Disease Models, Animal
Drug Therapy, Combination
Female
Fluconazole--pharmacology
Fungal Polysaccharides--antagonists & inhibitors
Hyphae--drug effects
Microbial Sensitivity Tests
Microbial Viability--drug effects
Nanoparticles--chemistry
Nitric Oxide--chemical synthesis
Nitric Oxide Donors--chemistry
Organosilicon Compounds--chemistry
Oxidation-Reduction
Rats
Rats, Sprague-Dawley
Sodium Nitrite--chemistry
Voriconazole--pharmacology