Rational steering of insulin binding specificity by intra-chain chemical crosslinking.

Viková, Jitka

Rational steering of insulin binding specificity by intra-chain chemical crosslinking. [electronic resource] - Scientific reports Jan 2016 - 19431 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2045-2322

10.1038/srep19431 doi


Alkynes--chemistry
Azides--chemistry
Cycloaddition Reaction
Humans
Insulin--chemistry
Models, Molecular
Protein Binding
Protein Conformation
Protein Isoforms
Protein Stability
Receptor, IGF Type 1--chemistry
Receptor, Insulin--chemistry
Structure-Activity Relationship