Treatment with atorvastatin attenuates progression of insulin resistance and pancreatic fibrosis in the Otsuka Long-Evans Tokushima fatty rats.

Wei, Limin

Treatment with atorvastatin attenuates progression of insulin resistance and pancreatic fibrosis in the Otsuka Long-Evans Tokushima fatty rats. [electronic resource] - Metabolism: clinical and experimental Feb 2016 - 41-53 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1532-8600

10.1016/j.metabol.2015.10.012 doi


Animals
Antioxidants--pharmacology
Apoptosis--drug effects
Atorvastatin--pharmacology
Body Weight--drug effects
Eating--drug effects
Fibrosis
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Insulin Resistance
Male
Oxidative Stress--drug effects
Pancreas--drug effects
Rats
Rats, Inbred OLETF
Transforming Growth Factor beta1--genetics