Lipoprotein LpqS deficient M. tuberculosis mutant is attenuated for virulence in vivo and shows protective efficacy better than BCG in guinea pigs.

Sakthi, Suba

Lipoprotein LpqS deficient M. tuberculosis mutant is attenuated for virulence in vivo and shows protective efficacy better than BCG in guinea pigs. [electronic resource] - Vaccine Feb 2016 - 735-43 p. digital

Publication Type: Journal Article

1873-2518

10.1016/j.vaccine.2015.12.059 doi


Animals
BCG Vaccine--immunology
Bacterial Load
Bacterial Proteins--genetics
Cytokines--immunology
Female
Gene Deletion
Guinea Pigs
Immunization--methods
Lipoproteins--genetics
Lung--microbiology
Mycobacterium tuberculosis--genetics
Spleen--microbiology
Tuberculosis Vaccines--immunology
Vaccines, Attenuated--immunology
Virulence