Molecular Mechanisms Responsible for Neuron-Derived Conditioned Medium (NCM)-Mediated Protection of Ischemic Brain.
Lin, Chi-Hsin
Molecular Mechanisms Responsible for Neuron-Derived Conditioned Medium (NCM)-Mediated Protection of Ischemic Brain. [electronic resource] - PloS one 2016 - e0146692 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0146692 doi
Animals
Apoptosis
Brain--blood supply
Cell Movement
Cell Survival
Cells, Cultured
Culture Media, Conditioned
Culture Media, Serum-Free
Drug Evaluation, Preclinical
Extracellular Signal-Regulated MAP Kinases--metabolism
Glial Cell Line-Derived Neurotrophic Factor--physiology
Infarction, Middle Cerebral Artery--drug therapy
Male
Microglia--physiology
Nerve Growth Factors--physiology
Neurons--metabolism
Neuroprotective Agents--administration & dosage
Oxidative Stress
Primary Cell Culture
Protective Factors
Rats, Sprague-Dawley
Reactive Oxygen Species--metabolism
Reperfusion Injury--prevention & control
Transforming Growth Factor beta1--physiology
Molecular Mechanisms Responsible for Neuron-Derived Conditioned Medium (NCM)-Mediated Protection of Ischemic Brain. [electronic resource] - PloS one 2016 - e0146692 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0146692 doi
Animals
Apoptosis
Brain--blood supply
Cell Movement
Cell Survival
Cells, Cultured
Culture Media, Conditioned
Culture Media, Serum-Free
Drug Evaluation, Preclinical
Extracellular Signal-Regulated MAP Kinases--metabolism
Glial Cell Line-Derived Neurotrophic Factor--physiology
Infarction, Middle Cerebral Artery--drug therapy
Male
Microglia--physiology
Nerve Growth Factors--physiology
Neurons--metabolism
Neuroprotective Agents--administration & dosage
Oxidative Stress
Primary Cell Culture
Protective Factors
Rats, Sprague-Dawley
Reactive Oxygen Species--metabolism
Reperfusion Injury--prevention & control
Transforming Growth Factor beta1--physiology