PLGA-Curcumin Attenuates Opioid-Induced Hyperalgesia and Inhibits Spinal CaMKIIα.

Hu, Xiaoyu

PLGA-Curcumin Attenuates Opioid-Induced Hyperalgesia and Inhibits Spinal CaMKIIα. [electronic resource] - PloS one 2016 - e0146393 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0146393 doi


Analgesics, Opioid--adverse effects
Animals
Calcium-Calmodulin-Dependent Protein Kinase Type 2--antagonists & inhibitors
Chronic Pain--drug therapy
Curcumin--chemistry
Drug Delivery Systems--methods
Drug Tolerance
Hyperalgesia--chemically induced
Lactic Acid--chemistry
Male
Mice
Mice, Inbred ICR
Morphine--adverse effects
Nanostructures--chemistry
Pain Measurement
Polyglycolic Acid--chemistry
Polylactic Acid-Polyglycolic Acid Copolymer
Spinal Cord Dorsal Horn--drug effects