Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling.

Coffey, Rory T

Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling. [electronic resource] - The Journal of biological chemistry Mar 2016 - 5221-33 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M115.691584 doi


Adaptor Proteins, Signal Transducing--metabolism
Arginine--analogs & derivatives
Carbamates--chemistry
Cell Cycle Proteins
Cell Line, Tumor
Cell Proliferation--drug effects
Enzyme Inhibitors--pharmacology
HEK293 Cells
Humans
Mechanistic Target of Rapamycin Complex 1
Multiprotein Complexes--metabolism
Phosphoproteins--metabolism
Phosphorylation
Protein Binding
Protein Biosynthesis
Protein Processing, Post-Translational
Ribosomal Protein S6 Kinases--metabolism
Signal Transduction
TOR Serine-Threonine Kinases--metabolism
Ubiquitins--antagonists & inhibitors