Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into β cells in mice with reversal of diabetes.
Zhang, Mingfeng
Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into β cells in mice with reversal of diabetes. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jan 2016 - 650-5 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1091-6490
10.1073/pnas.1524200113 doi
Animals
Blood Glucose--metabolism
Cell Differentiation--drug effects
Culture Media--chemistry
Diabetes Mellitus, Experimental--pathology
Epidermal Growth Factor--administration & dosage
Gastrins--administration & dosage
Hyperglycemia--complications
Insulin-Secreting Cells--pathology
Kinetics
Mice, Inbred C57BL
Pancreatic Ducts--pathology
SOX9 Transcription Factor--metabolism
Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into β cells in mice with reversal of diabetes. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jan 2016 - 650-5 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1091-6490
10.1073/pnas.1524200113 doi
Animals
Blood Glucose--metabolism
Cell Differentiation--drug effects
Culture Media--chemistry
Diabetes Mellitus, Experimental--pathology
Epidermal Growth Factor--administration & dosage
Gastrins--administration & dosage
Hyperglycemia--complications
Insulin-Secreting Cells--pathology
Kinetics
Mice, Inbred C57BL
Pancreatic Ducts--pathology
SOX9 Transcription Factor--metabolism