Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis.

Maxson, Julia E

Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis. [electronic resource] - Cancer research Jan 2016 - 127-38 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1538-7445

10.1158/0008-5472.CAN-15-0817 doi


Animals
Base Sequence
Cell Line, Tumor
Drug Screening Assays, Antitumor--methods
Female
Genomics
HEK293 Cells
Humans
Leukemia, Myeloid, Acute--drug therapy
Male
Mice
Models, Molecular
Point Mutation
Protein Kinase Inhibitors--pharmacology
Protein-Tyrosine Kinases--antagonists & inhibitors
Transfection