Induction of cell cycle arrest via the p21, p27-cyclin E,A/Cdk2 pathway in SMMC-7721 hepatoma cells by clioquinol.

Huang, Zhiwei

Induction of cell cycle arrest via the p21, p27-cyclin E,A/Cdk2 pathway in SMMC-7721 hepatoma cells by clioquinol. [electronic resource] - Acta pharmaceutica (Zagreb, Croatia) Dec 2015 - 463-71 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1846-9558

10.1515/acph-2015-0034 doi


Antineoplastic Agents--pharmacology
Carcinoma, Hepatocellular--drug therapy
Cell Line, Tumor
Cell Survival--drug effects
Clioquinol--pharmacology
Cyclin A2--genetics
Cyclin E--genetics
Cyclin-Dependent Kinase 2--genetics
Cyclin-Dependent Kinase Inhibitor p21--genetics
Cyclin-Dependent Kinase Inhibitor p27--genetics
Dose-Response Relationship, Drug
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Neoplastic
Humans
Liver Neoplasms--drug therapy
Oncogene Proteins--genetics
S Phase Cell Cycle Checkpoints--drug effects
Signal Transduction--drug effects
Time Factors