Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin.

Korneeva, Nadejda L

Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin. [electronic resource] - The Journal of biological chemistry Feb 2016 - 3455-67 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1083-351X

10.1074/jbc.M115.694190 doi


Amino Acid Substitution
Animals
Cell-Free System--drug effects
Eukaryotic Initiation Factor-4E--chemistry
Eukaryotic Initiation Factor-4G--chemistry
Humans
Intracellular Signaling Peptides and Proteins--antagonists & inhibitors
Inverted Repeat Sequences
Mutant Proteins--antagonists & inhibitors
Peptide Fragments--antagonists & inhibitors
Phosphorylation--drug effects
Protein Biosynthesis--drug effects
Protein Interaction Domains and Motifs
Protein Kinase Inhibitors--pharmacology
Protein Processing, Post-Translational--drug effects
Protein Serine-Threonine Kinases--antagonists & inhibitors
RNA--chemistry
RNA Caps--chemistry
RNA Folding--drug effects
RNA, Messenger--chemistry
Rabbits
Recombinant Proteins--chemistry
Reticulocytes--drug effects