Establishment of an Animal Model of Bisphosphonate-Related Osteonecrosis of the Jaws in Spontaneously Diabetic Torii Rats.

Takaoka, Kazuki

Establishment of an Animal Model of Bisphosphonate-Related Osteonecrosis of the Jaws in Spontaneously Diabetic Torii Rats. [electronic resource] - PloS one 2015 - e0144355 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0144355 doi


Acid Phosphatase--genetics
Animals
Bisphosphonate-Associated Osteonecrosis of the Jaw--complications
Bone Density
Bone Remodeling
Diabetes Mellitus, Type 2--complications
Diphosphonates--adverse effects
Disease Models, Animal
Gene Expression
Humans
Imidazoles--adverse effects
Injections, Intravenous
Isoenzymes--genetics
Male
Maxilla--metabolism
Molar--metabolism
Osteoclasts--metabolism
Rats
Rats, Sprague-Dawley
Rats, Transgenic
Tartrate-Resistant Acid Phosphatase
Tooth Extraction
Zoledronic Acid