MULTIMERIN2 binds VEGF-A primarily via the carbohydrate chains exerting an angiostatic function and impairing tumor growth.

Colladel, Roberta

MULTIMERIN2 binds VEGF-A primarily via the carbohydrate chains exerting an angiostatic function and impairing tumor growth. [electronic resource] - Oncotarget Jan 2016 - 2022-37 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1949-2553

10.18632/oncotarget.6515 doi


Animals
Antigens, Surface--metabolism
Apoptosis
Carbohydrates--chemistry
Cell Movement
Cell Proliferation
Female
Fibrosarcoma--blood supply
Fluorescent Antibody Technique
Glycosylation
Human Umbilical Vein Endothelial Cells--metabolism
Humans
Immunoenzyme Techniques
Membrane Glycoproteins--metabolism
Mice
Mice, Inbred BALB C
Mice, Nude
Neovascularization, Pathologic--prevention & control
Phosphorylation
RNA, Messenger--genetics
Real-Time Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
Surface Plasmon Resonance
Tumor Cells, Cultured
Vascular Endothelial Growth Factor A--metabolism
Xenograft Model Antitumor Assays