Addressing cytotoxicity of 1,4-biphenyl amide derivatives: Discovery of new potent and selective 17β-hydroxysteroid dehydrogenase type 2 inhibitors.
Gargano, Emanuele Marco
Addressing cytotoxicity of 1,4-biphenyl amide derivatives: Discovery of new potent and selective 17β-hydroxysteroid dehydrogenase type 2 inhibitors. [electronic resource] - Bioorganic & medicinal chemistry letters Jan 2016 - 21-4 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3405
10.1016/j.bmcl.2015.11.047 doi
Amides--chemical synthesis
Biphenyl Compounds--chemical synthesis
Cell Survival--drug effects
Cytotoxins--chemical synthesis
Dose-Response Relationship, Drug
Drug Discovery
Enzyme Inhibitors--chemical synthesis
Estradiol Dehydrogenases--antagonists & inhibitors
HEK293 Cells
Humans
Molecular Structure
Structure-Activity Relationship
Addressing cytotoxicity of 1,4-biphenyl amide derivatives: Discovery of new potent and selective 17β-hydroxysteroid dehydrogenase type 2 inhibitors. [electronic resource] - Bioorganic & medicinal chemistry letters Jan 2016 - 21-4 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3405
10.1016/j.bmcl.2015.11.047 doi
Amides--chemical synthesis
Biphenyl Compounds--chemical synthesis
Cell Survival--drug effects
Cytotoxins--chemical synthesis
Dose-Response Relationship, Drug
Drug Discovery
Enzyme Inhibitors--chemical synthesis
Estradiol Dehydrogenases--antagonists & inhibitors
HEK293 Cells
Humans
Molecular Structure
Structure-Activity Relationship