Targeting Two Coagulation Cascade Proteases with a Bivalent Aptamer Yields a Potent and Antidote-Controllable Anticoagulant.

Soule, Erin E

Targeting Two Coagulation Cascade Proteases with a Bivalent Aptamer Yields a Potent and Antidote-Controllable Anticoagulant. [electronic resource] - Nucleic acid therapeutics Feb 2016 - 1-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

2159-3345

10.1089/nat.2015.0565 doi


Anticoagulants--pharmacology
Antidotes--pharmacology
Aptamers, Nucleotide--chemistry
Base Sequence
Blood Coagulation Factors--genetics
Humans
Molecular Sequence Data
Nucleic Acid Conformation
Serine Proteases--genetics