Identification of a Novel Heart-Liver Axis: Matrix Metalloproteinase-2 Negatively Regulates Cardiac Secreted Phospholipase A2 to Modulate Lipid Metabolism and Inflammation in the Liver.

Hernandez-Anzaldo, Samuel

Identification of a Novel Heart-Liver Axis: Matrix Metalloproteinase-2 Negatively Regulates Cardiac Secreted Phospholipase A2 to Modulate Lipid Metabolism and Inflammation in the Liver. [electronic resource] - Journal of the American Heart Association Nov 2015

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2047-9980

10.1161/JAHA.115.002553 doi


Acetates--pharmacology
Animals
Antibodies--pharmacology
Cells, Cultured
Chemokine CCL7--antagonists & inhibitors
Cholesterol, Dietary--metabolism
Enzyme Inhibitors--pharmacology
Gene Expression Regulation
Genetic Predisposition to Disease
Hepatitis--enzymology
Indoles--pharmacology
Keto Acids
Lipid Metabolism--drug effects
Liver--drug effects
Matrix Metalloproteinase 2--deficiency
Mice, Inbred C57BL
Mice, Knockout
Myocytes, Cardiac--drug effects
Phenotype
Phospholipases A2, Secretory--antagonists & inhibitors
Signal Transduction
Time Factors
Transcription, Genetic
Triglycerides--metabolism