Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner.

Lowin, Torsten

Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner. [electronic resource] - Arthritis research & therapy Nov 2015 - 321 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1478-6362

10.1186/s13075-015-0845-5 doi


Aged
Animals
Anti-Inflammatory Agents--pharmacology
Arthritis, Rheumatoid--metabolism
Calcium Channels--physiology
Cells, Cultured
Cyclooxygenase 2--physiology
Cyclooxygenase 2 Inhibitors--pharmacology
Dose-Response Relationship, Drug
Ethanolamines--pharmacology
Female
Humans
Inflammation Mediators--metabolism
Male
Mice
Mice, Inbred DBA
Middle Aged
Nerve Tissue Proteins--physiology
Synovial Membrane--cytology
TRPA1 Cation Channel
TRPV Cation Channels--physiology
Transient Receptor Potential Channels--physiology