Iron overload results in hepatic oxidative stress, immune cell activation, and hepatocellular ballooning injury, leading to nonalcoholic steatohepatitis in genetically obese mice.
Handa, Priya
Iron overload results in hepatic oxidative stress, immune cell activation, and hepatocellular ballooning injury, leading to nonalcoholic steatohepatitis in genetically obese mice. [electronic resource] - American journal of physiology. Gastrointestinal and liver physiology Jan 2016 - G117-27 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1522-1547
10.1152/ajpgi.00246.2015 doi
Adaptive Immunity--genetics
Animals
Disease Models, Animal
Immunity, Innate--genetics
Iron Overload--complications
Liver--metabolism
Malondialdehyde--metabolism
Mice
Mice, Obese
Non-alcoholic Fatty Liver Disease--etiology
Obesity--complications
Oxidative Stress--physiology
Reactive Oxygen Species--metabolism
Receptors, Leptin--genetics
Iron overload results in hepatic oxidative stress, immune cell activation, and hepatocellular ballooning injury, leading to nonalcoholic steatohepatitis in genetically obese mice. [electronic resource] - American journal of physiology. Gastrointestinal and liver physiology Jan 2016 - G117-27 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1522-1547
10.1152/ajpgi.00246.2015 doi
Adaptive Immunity--genetics
Animals
Disease Models, Animal
Immunity, Innate--genetics
Iron Overload--complications
Liver--metabolism
Malondialdehyde--metabolism
Mice
Mice, Obese
Non-alcoholic Fatty Liver Disease--etiology
Obesity--complications
Oxidative Stress--physiology
Reactive Oxygen Species--metabolism
Receptors, Leptin--genetics