Mutants of human colon adenocarcinoma, selected for thymidylate synthase deficiency.

Houghton, P J

Mutants of human colon adenocarcinoma, selected for thymidylate synthase deficiency. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Feb 1989 - 1377-81 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.86.4.1377 doi


Adenocarcinoma--enzymology
Animals
Cell Division
Cell Line
Cell Survival
Clone Cells
Colonic Neoplasms--enzymology
DNA Replication
Deoxyuridine--metabolism
Humans
Kinetics
Mice
Mutation
Neoplasm Transplantation
Nucleoside-Phosphate Kinase--metabolism
Thymidine--metabolism
Thymidylate Synthase--deficiency
Transplantation, Heterologous
Tumor Cells, Cultured--cytology