LXR Agonism Upregulates the Macrophage ABCA1/Syntrophin Protein Complex That Can Bind ApoA-I and Stabilized ABCA1 Protein, but Complex Loss Does Not Inhibit Lipid Efflux.

Tamehiro, Norimasa

LXR Agonism Upregulates the Macrophage ABCA1/Syntrophin Protein Complex That Can Bind ApoA-I and Stabilized ABCA1 Protein, but Complex Loss Does Not Inhibit Lipid Efflux. [electronic resource] - Biochemistry Nov 2015 - 6931-41 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1520-4995

10.1021/acs.biochem.5b00894 doi


ATP Binding Cassette Transporter 1--deficiency
Animals
Apolipoprotein A-I--metabolism
Biological Transport, Active
Calcium-Binding Proteins--deficiency
Cell Line
Dystrophin-Associated Proteins--deficiency
Hydrocarbons, Fluorinated--pharmacology
Lipid Metabolism
Liver X Receptors
Macrophages--drug effects
Membrane Proteins--deficiency
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Mice, Knockout
Multiprotein Complexes--chemistry
Muscle Proteins--deficiency
Orphan Nuclear Receptors--agonists
Protein Binding
Protein Interaction Domains and Motifs
Protein Stability
RNA, Messenger--genetics
Sulfonamides--pharmacology
Up-Regulation