Loss of Nek11 Prevents G2/M Arrest and Promotes Cell Death in HCT116 Colorectal Cancer Cells Exposed to Therapeutic DNA Damaging Agents.

Sabir, Sarah R

Loss of Nek11 Prevents G2/M Arrest and Promotes Cell Death in HCT116 Colorectal Cancer Cells Exposed to Therapeutic DNA Damaging Agents. [electronic resource] - PloS one 2015 - e0140975 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0140975 doi


Active Transport, Cell Nucleus--genetics
Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis--drug effects
Camptothecin--analogs & derivatives
Cell Death--drug effects
Cell Survival--physiology
Colorectal Neoplasms--drug therapy
DNA Damage--drug effects
G2 Phase Cell Cycle Checkpoints--drug effects
HCT116 Cells--drug effects
Humans
Irinotecan
M Phase Cell Cycle Checkpoints--drug effects
NIMA-Related Kinases
Protein Kinases--physiology
RNA Interference