Absorption of ipratropium and l-carnitine into the pulmonary circulation of the ex-vivo rat lung is driven by passive processes rather than active uptake by OCT/OCTN transporters.

Al-Jayyoussi, Ghaith

Absorption of ipratropium and l-carnitine into the pulmonary circulation of the ex-vivo rat lung is driven by passive processes rather than active uptake by OCT/OCTN transporters. [electronic resource] - International journal of pharmaceutics Dec 2015 - 834-41 p. digital

Publication Type: Journal Article

1873-3476

10.1016/j.ijpharm.2015.10.036 doi


Animals
Carnitine--pharmacokinetics
Carrier Proteins--physiology
Cells, Cultured
Epithelial Cells--metabolism
Humans
Ipratropium--pharmacokinetics
Lung--metabolism
Membrane Proteins--physiology
Organic Cation Transport Proteins--physiology
Pulmonary Circulation
Rats
Solute Carrier Family 22 Member 5
Solute Carrier Proteins
Symporters