Targeting the ∆133p53 isoform can restore chemosensitivity in 5-fluorouracil-resistant cholangiocarcinoma cells.

Nutthasirikul, Nichapavee

Targeting the ∆133p53 isoform can restore chemosensitivity in 5-fluorouracil-resistant cholangiocarcinoma cells. [electronic resource] - International journal of oncology Dec 2015 - 2153-64 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1791-2423

10.3892/ijo.2015.3188 doi


Aged
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Bile Duct Neoplasms--drug therapy
Blotting, Western
Cell Line, Tumor
Cell Proliferation--drug effects
Cholangiocarcinoma--drug therapy
Drug Resistance, Neoplasm--genetics
Female
Fluorouracil--pharmacology
Gene Knockdown Techniques
Humans
Immunohistochemistry
Inhibitory Concentration 50
Male
Middle Aged
Protein Isoforms
RNA, Small Interfering
Transfection
Tumor Suppressor Protein p53--genetics