Dendritic Spine Instability in a Mouse Model of CDKL5 Disorder Is Rescued by Insulin-like Growth Factor 1.
Della Sala, Grazia
Dendritic Spine Instability in a Mouse Model of CDKL5 Disorder Is Rescued by Insulin-like Growth Factor 1. [electronic resource] - Biological psychiatry 08 2016 - 302-311 p. digital
Publication Type: Journal Article
1873-2402
10.1016/j.biopsych.2015.08.028 doi
Age Factors
Animals
Animals, Newborn
Dendritic Spines--drug effects
Disease Models, Animal
Disks Large Homolog 4 Protein
Epileptic Syndromes
Gene Expression Regulation, Developmental--drug effects
Green Fluorescent Proteins--genetics
Guanylate Kinases--metabolism
Insulin-Like Growth Factor I--therapeutic use
Long-Term Potentiation--drug effects
Membrane Proteins--metabolism
Mice
Mice, Transgenic
Patch-Clamp Techniques
Phosphorylation--drug effects
Protein Serine-Threonine Kinases--deficiency
Pyramidal Cells--pathology
Rett Syndrome--drug therapy
Somatosensory Cortex--pathology
Spasms, Infantile--drug therapy
Synapses--drug effects
Dendritic Spine Instability in a Mouse Model of CDKL5 Disorder Is Rescued by Insulin-like Growth Factor 1. [electronic resource] - Biological psychiatry 08 2016 - 302-311 p. digital
Publication Type: Journal Article
1873-2402
10.1016/j.biopsych.2015.08.028 doi
Age Factors
Animals
Animals, Newborn
Dendritic Spines--drug effects
Disease Models, Animal
Disks Large Homolog 4 Protein
Epileptic Syndromes
Gene Expression Regulation, Developmental--drug effects
Green Fluorescent Proteins--genetics
Guanylate Kinases--metabolism
Insulin-Like Growth Factor I--therapeutic use
Long-Term Potentiation--drug effects
Membrane Proteins--metabolism
Mice
Mice, Transgenic
Patch-Clamp Techniques
Phosphorylation--drug effects
Protein Serine-Threonine Kinases--deficiency
Pyramidal Cells--pathology
Rett Syndrome--drug therapy
Somatosensory Cortex--pathology
Spasms, Infantile--drug therapy
Synapses--drug effects